4,4'-DIAMINODIPHENYLAMINE

Banned in specific cases CAS: 537-65-5CosIng #31520

4,4'-DIAMINODIPHENYLAMINE must not be used as a substance in hair dye products in the EU — Annex II, entry 1309 of Regulation (EC) No 1223/2009. The prohibition is limited to that use; the entry is quoted in full below.

Regulatory data checked on 2026-09-05. The legal status follows Regulation (EC) No 1223/2009 and its annexes; the substance is identified from the European Commission's CosIng database.

About the ingredient

4,4'-iminodianiline (CI 76120)

EU regulatory status

Annex of Regulation (EC) No 1223/2009: II/1309

4,4'-Diaminodiphenylamine and its salts, when used as a substance in hair dye products

Source: the European Commission's official CosIng database and Regulation (EC) No 1223/2009 of the European Parliament and of the Council on cosmetic products. How we assess ingredients — full methodology.

Last updated:

Functions in cosmetics

Frequently asked questions

  • Is 4,4'-DIAMINODIPHENYLAMINE safe in cosmetics?

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  • In which annex of Regulation 1223/2009 does 4,4'-DIAMINODIPHENYLAMINE fall?

    4,4'-DIAMINODIPHENYLAMINE falls under reference II/1309 in the annexes of Regulation (EC) No 1223/2009 on cosmetic products. An annex entry may name a substance directly or cover it as part of a broader category. The first part (Roman numeral) indicates the annex: II – prohibited substances, III – substances restricted by conditions, IV – permitted colorants, V – permitted preservatives, VI – permitted UV filters.

  • What functions does 4,4'-DIAMINODIPHENYLAMINE perform in cosmetics?

    According to the European Commission's CosIng database, 4,4'-DIAMINODIPHENYLAMINE performs the following functions in cosmetics: HAIR DYEING. Functions are defined in the CosIng glossary and describe the technological role of a substance in the finished product.

  • Are there Safety Gate alerts concerning 4,4'-DIAMINODIPHENYLAMINE?

    Our copy of the EU Safety Gate database currently contains no alerts linking 4,4'-DIAMINODIPHENYLAMINE to a cosmetic recall. The database is refreshed regularly from the European Commission's official Safety Gate system.

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