6-NITRO-2,5-PYRIDINEDIAMINE
6-NITRO-2,5-PYRIDINEDIAMINE must not be used as a substance in hair dye products in the EU — Annex II, entry 1321 of Regulation (EC) No 1223/2009. The prohibition is limited to that use; the entry is quoted in full below.
Regulatory data checked on 2026-09-05. The legal status follows Regulation (EC) No 1223/2009 and its annexes; the substance is identified from the European Commission's CosIng database.
About the ingredient
2,5-diamino-6-nitro-pyridine
EU regulatory status
Annex of Regulation (EC) No 1223/2009: II/1321
What entry II/1321 of the Regulation says
6-Nitro-2,5-pyridinediamine and its salts, when used as a substance in hair dye products
Source: the European Commission's official CosIng database and Regulation (EC) No 1223/2009 of the European Parliament and of the Council on cosmetic products. How we assess ingredients — full methodology.
- View the entry in the CosIng database (European Commission)
- Open Regulation 1223/2009 in EUR-Lex
- Check the chemical profile in PubChem
Last updated:
Functions in cosmetics
Frequently asked questions
Is 6-NITRO-2,5-PYRIDINEDIAMINE safe in cosmetics?
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In which annex of Regulation 1223/2009 does 6-NITRO-2,5-PYRIDINEDIAMINE fall?
6-NITRO-2,5-PYRIDINEDIAMINE falls under reference II/1321 in the annexes of Regulation (EC) No 1223/2009 on cosmetic products. An annex entry may name a substance directly or cover it as part of a broader category. The first part (Roman numeral) indicates the annex: II – prohibited substances, III – substances restricted by conditions, IV – permitted colorants, V – permitted preservatives, VI – permitted UV filters.
What functions does 6-NITRO-2,5-PYRIDINEDIAMINE perform in cosmetics?
According to the European Commission's CosIng database, 6-NITRO-2,5-PYRIDINEDIAMINE performs the following functions in cosmetics: HAIR DYEING. Functions are defined in the CosIng glossary and describe the technological role of a substance in the finished product.
Are there Safety Gate alerts concerning 6-NITRO-2,5-PYRIDINEDIAMINE?
Our copy of the EU Safety Gate database currently contains no alerts linking 6-NITRO-2,5-PYRIDINEDIAMINE to a cosmetic recall. The database is refreshed regularly from the European Commission's official Safety Gate system.