BENZETHONIUM CHLORIDE

Annex IV–VI CAS: 121-54-0CosIng #32132

BENZETHONIUM CHLORIDE is approved in cosmetics in the EU as a preservative — Annex V, entry 53 of Regulation (EC) No 1223/2009. Review the concentration limits and Safety Gate alerts.

Regulatory status as of 2026-08-28 (per the CosIng database).

About the ingredient

Benzenemethanaminium, N,N-dimethyl-N-[2-[2-[4-(1,1,3,3,-tetramethylbutyl)phenoxy]ethoxy]ethyl]-, chloride

EU regulatory status

Annex of Regulation (EC) No 1223/2009: V/53

Source: the European Commission's official CosIng database and Regulation (EC) No 1223/2009 of the European Parliament and of the Council on cosmetic products. How we assess ingredients — full methodology.

Last updated:

Functions in cosmetics

Frequently asked questions

  • Is BENZETHONIUM CHLORIDE safe in cosmetics?

    BENZETHONIUM CHLORIDE is included on the EU positive list of special-purpose additives (Annex IV – colorants, Annex V – preservatives, or Annex VI – UV filters of Regulation (EC) No 1223/2009). It may be used in cosmetics under the conditions laid down for the relevant annex: permitted product categories, maximum concentration and required warnings.

  • In which annex of Regulation 1223/2009 is BENZETHONIUM CHLORIDE listed?

    BENZETHONIUM CHLORIDE is listed under reference V/53 in the annexes of Regulation (EC) No 1223/2009 on cosmetic products. The first part (Roman numeral) indicates the annex: II – prohibited substances, III – substances restricted by conditions, IV – permitted colorants, V – permitted preservatives, VI – permitted UV filters.

  • What functions does BENZETHONIUM CHLORIDE perform in cosmetics?

    According to the European Commission's CosIng database, BENZETHONIUM CHLORIDE performs the following functions in cosmetics: ANTIMICROBIAL, DEODORANT, PRESERVATIVE, SURFACTANT - DISPERSING. Functions are defined in the CosIng glossary and describe the technological role of a substance in the finished product.

  • Are there Safety Gate alerts concerning BENZETHONIUM CHLORIDE?

    Our copy of the EU Safety Gate database currently contains no alerts linking BENZETHONIUM CHLORIDE to a cosmetic recall. The database is refreshed regularly from the European Commission's official Safety Gate system.

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