HUMAN AMNIOTIC FLUID MESENCHYMAL STEM CELL/TROPHOBLAST CELL EXOSOMES
HUMAN AMNIOTIC FLUID MESENCHYMAL STEM CELL/TROPHOBLAST CELL EXOSOMES is banned in cosmetics in the EU — Annex II, entry 416 of Regulation (EC) No 1223/2009. Review the regulatory details and Safety Gate alerts.
Regulatory status as of 2026-08-28 (per the CosIng database).
About the ingredient
Human Amniotic Fluid Mesenchymal Stem Cell/Trophoblast Cell Exosomes are vesicles that are secreted into the conditioned media by human amniotic fluid mesenchymal stem cells and human trophoblast cells.
EU regulatory status
Annex of Regulation (EC) No 1223/2009: II/416
Source: the European Commission's official CosIng database and Regulation (EC) No 1223/2009 of the European Parliament and of the Council on cosmetic products. How we assess ingredients — full methodology.
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Functions in cosmetics
Frequently asked questions
Is HUMAN AMNIOTIC FLUID MESENCHYMAL STEM CELL/TROPHOBLAST CELL EXOSOMES safe in cosmetics?
HUMAN AMNIOTIC FLUID MESENCHYMAL STEM CELL/TROPHOBLAST CELL EXOSOMES is banned in the EU under Annex II of Regulation (EC) No 1223/2009 and may not be used in cosmetics placed on the EU market. Cosmetics containing this substance are withdrawn by national inspectorates and reported to the EU Safety Gate database.
In which annex of Regulation 1223/2009 is HUMAN AMNIOTIC FLUID MESENCHYMAL STEM CELL/TROPHOBLAST CELL EXOSOMES listed?
HUMAN AMNIOTIC FLUID MESENCHYMAL STEM CELL/TROPHOBLAST CELL EXOSOMES is listed under reference II/416 in the annexes of Regulation (EC) No 1223/2009 on cosmetic products. The first part (Roman numeral) indicates the annex: II – prohibited substances, III – substances restricted by conditions, IV – permitted colorants, V – permitted preservatives, VI – permitted UV filters.
What functions does HUMAN AMNIOTIC FLUID MESENCHYMAL STEM CELL/TROPHOBLAST CELL EXOSOMES perform in cosmetics?
According to the European Commission's CosIng database, HUMAN AMNIOTIC FLUID MESENCHYMAL STEM CELL/TROPHOBLAST CELL EXOSOMES performs the following functions in cosmetics: SKIN CONDITIONING. Functions are defined in the CosIng glossary and describe the technological role of a substance in the finished product.
Are there Safety Gate alerts concerning HUMAN AMNIOTIC FLUID MESENCHYMAL STEM CELL/TROPHOBLAST CELL EXOSOMES?
Our copy of the EU Safety Gate database currently contains no alerts linking HUMAN AMNIOTIC FLUID MESENCHYMAL STEM CELL/TROPHOBLAST CELL EXOSOMES to a cosmetic recall. The database is refreshed regularly from the European Commission's official Safety Gate system.