HUMAN URINE DERIVED INDUCED PLURIPOTENT CELL CULTURE CONDITIONED MEDIA
HUMAN URINE DERIVED INDUCED PLURIPOTENT CELL CULTURE CONDITIONED MEDIA is banned in cosmetics in the EU — Annex II, entry 416 of Regulation (EC) No 1223/2009. Review the regulatory details and Safety Gate alerts.
Regulatory status as of 2026-08-28 (per the CosIng database).
About the ingredient
Human Urine Derived Induced Pluripotent Cell Culture Conditioned Media is the growth media removed from cultures of induced pluripotent cells isolated from human urine after several days of growth.
EU regulatory status
Annex of Regulation (EC) No 1223/2009: II/416
Source: the European Commission's official CosIng database and Regulation (EC) No 1223/2009 of the European Parliament and of the Council on cosmetic products. How we assess ingredients — full methodology.
Last updated:
Functions in cosmetics
Frequently asked questions
Is HUMAN URINE DERIVED INDUCED PLURIPOTENT CELL CULTURE CONDITIONED MEDIA safe in cosmetics?
HUMAN URINE DERIVED INDUCED PLURIPOTENT CELL CULTURE CONDITIONED MEDIA is banned in the EU under Annex II of Regulation (EC) No 1223/2009 and may not be used in cosmetics placed on the EU market. Cosmetics containing this substance are withdrawn by national inspectorates and reported to the EU Safety Gate database.
In which annex of Regulation 1223/2009 is HUMAN URINE DERIVED INDUCED PLURIPOTENT CELL CULTURE CONDITIONED MEDIA listed?
HUMAN URINE DERIVED INDUCED PLURIPOTENT CELL CULTURE CONDITIONED MEDIA is listed under reference II/416 in the annexes of Regulation (EC) No 1223/2009 on cosmetic products. The first part (Roman numeral) indicates the annex: II – prohibited substances, III – substances restricted by conditions, IV – permitted colorants, V – permitted preservatives, VI – permitted UV filters.
What functions does HUMAN URINE DERIVED INDUCED PLURIPOTENT CELL CULTURE CONDITIONED MEDIA perform in cosmetics?
According to the European Commission's CosIng database, HUMAN URINE DERIVED INDUCED PLURIPOTENT CELL CULTURE CONDITIONED MEDIA performs the following functions in cosmetics: HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT. Functions are defined in the CosIng glossary and describe the technological role of a substance in the finished product.
Are there Safety Gate alerts concerning HUMAN URINE DERIVED INDUCED PLURIPOTENT CELL CULTURE CONDITIONED MEDIA?
Our copy of the EU Safety Gate database currently contains no alerts linking HUMAN URINE DERIVED INDUCED PLURIPOTENT CELL CULTURE CONDITIONED MEDIA to a cosmetic recall. The database is refreshed regularly from the European Commission's official Safety Gate system.