OLIGOPEPTIDE-164
OLIGOPEPTIDE-164 is permitted in cosmetics within the EU subject to the conditions laid down in Regulation (EC) No 1223/2009. Review the restrictions, permitted concentration and Safety Gate alerts.
Regulatory status as of 2026-08-28 (per the CosIng database).
About the ingredient
Oligopeptide-164 is a synthetic peptide containing 11 amino acids consisting of alanine, histidine, isoleucine, leucine, methionine, proline and valine.
EU regulatory status
Annex of Regulation (EC) No 1223/2009: Oligopeptide-164 is included in the INCI database as a reference for the definition of other INCI Names, and might not be a marketed cosmetic ingredient.
Source: the European Commission's official CosIng database and Regulation (EC) No 1223/2009 of the European Parliament and of the Council on cosmetic products. How we assess ingredients — full methodology.
Last updated:
Functions in cosmetics
Frequently asked questions
Is OLIGOPEPTIDE-164 safe in cosmetics?
OLIGOPEPTIDE-164 is permitted in cosmetics in the EU, but subject to the conditions set out in Regulation (EC) No 1223/2009 — typically a maximum concentration, product category or a mandatory warning on the packaging. Manufacturers must comply with these limits.
In which annex of Regulation 1223/2009 is OLIGOPEPTIDE-164 listed?
OLIGOPEPTIDE-164 is listed under reference Oligopeptide-164 is included in the INCI database as a reference for the definition of other INCI Names, and might not be a marketed cosmetic ingredient. in the annexes of Regulation (EC) No 1223/2009 on cosmetic products. The first part (Roman numeral) indicates the annex: II – prohibited substances, III – substances restricted by conditions, IV – permitted colorants, V – permitted preservatives, VI – permitted UV filters.
What functions does OLIGOPEPTIDE-164 perform in cosmetics?
According to the European Commission's CosIng database, OLIGOPEPTIDE-164 performs the following functions in cosmetics: NOT REPORTED. Functions are defined in the CosIng glossary and describe the technological role of a substance in the finished product.
Are there Safety Gate alerts concerning OLIGOPEPTIDE-164?
Our copy of the EU Safety Gate database currently contains no alerts linking OLIGOPEPTIDE-164 to a cosmetic recall. The database is refreshed regularly from the European Commission's official Safety Gate system.