POLYQUATERNIUM-43
POLYQUATERNIUM-43 is permitted in cosmetics in the EU with restrictions — Annex III, entry 66 of Regulation (EC) No 1223/2009. Review the conditions of use, permitted concentration and Safety Gate alerts.
Regulatory data checked on 2026-09-05. The legal status follows Regulation (EC) No 1223/2009 and its annexes; the substance is identified from the European Commission's CosIng database.
About the ingredient
Polyquaternium-43 is the polymeric quaternary ammonium salt formed from acrylamide, acrylamidopropyltrimonium chloride, 2-amidopropylacrylamide sulfonate, and DMAPA monomers
EU regulatory status
Annex of Regulation (EC) No 1223/2009: III/66
What entry III/66 of the Regulation says
Polyacrylamides
Source: the European Commission's official CosIng database and Regulation (EC) No 1223/2009 of the European Parliament and of the Council on cosmetic products. How we assess ingredients — full methodology.
Last updated:
Functions in cosmetics
Frequently asked questions
Is POLYQUATERNIUM-43 safe in cosmetics?
POLYQUATERNIUM-43 is permitted in cosmetics in the EU, but subject to the conditions set out in Regulation (EC) No 1223/2009 — typically a maximum concentration, product category or a mandatory warning on the packaging. Manufacturers must comply with these limits.
In which annex of Regulation 1223/2009 does POLYQUATERNIUM-43 fall?
POLYQUATERNIUM-43 falls under reference III/66 in the annexes of Regulation (EC) No 1223/2009 on cosmetic products. An annex entry may name a substance directly or cover it as part of a broader category. The first part (Roman numeral) indicates the annex: II – prohibited substances, III – substances restricted by conditions, IV – permitted colorants, V – permitted preservatives, VI – permitted UV filters.
What functions does POLYQUATERNIUM-43 perform in cosmetics?
According to the European Commission's CosIng database, POLYQUATERNIUM-43 performs the following functions in cosmetics: ANTISTATIC, FILM FORMING. Functions are defined in the CosIng glossary and describe the technological role of a substance in the finished product.
Are there Safety Gate alerts concerning POLYQUATERNIUM-43?
Our copy of the EU Safety Gate database currently contains no alerts linking POLYQUATERNIUM-43 to a cosmetic recall. The database is refreshed regularly from the European Commission's official Safety Gate system.