TETRAAMINOPYRIMIDINE SULFATE

Restricted CAS: 5392-28-9CosIng #60226

TETRAAMINOPYRIMIDINE SULFATE is permitted in cosmetics within the EU subject to the conditions laid down in Regulation (EC) No 1223/2009. Review the restrictions, permitted concentration and Safety Gate alerts.

Regulatory status as of 2026-08-28 (per the CosIng database).

About the ingredient

Pyrimidine tetramine, sulfate (1:1); Pyrimidinetetrayltetraamine sulphate

EU regulatory status

Annex of Regulation (EC) No 1223/2009: Annex III/200

Source: the European Commission's official CosIng database and Regulation (EC) No 1223/2009 of the European Parliament and of the Council on cosmetic products. How we assess ingredients — full methodology.

Last updated:

Functions in cosmetics

Frequently asked questions

  • Is TETRAAMINOPYRIMIDINE SULFATE safe in cosmetics?

    TETRAAMINOPYRIMIDINE SULFATE is permitted in cosmetics in the EU, but subject to the conditions set out in Regulation (EC) No 1223/2009 — typically a maximum concentration, product category or a mandatory warning on the packaging. Manufacturers must comply with these limits.

  • In which annex of Regulation 1223/2009 is TETRAAMINOPYRIMIDINE SULFATE listed?

    TETRAAMINOPYRIMIDINE SULFATE is listed under reference Annex III/200 in the annexes of Regulation (EC) No 1223/2009 on cosmetic products. The first part (Roman numeral) indicates the annex: II – prohibited substances, III – substances restricted by conditions, IV – permitted colorants, V – permitted preservatives, VI – permitted UV filters.

  • What functions does TETRAAMINOPYRIMIDINE SULFATE perform in cosmetics?

    According to the European Commission's CosIng database, TETRAAMINOPYRIMIDINE SULFATE performs the following functions in cosmetics: HAIR DYEING. Functions are defined in the CosIng glossary and describe the technological role of a substance in the finished product.

  • Are there Safety Gate alerts concerning TETRAAMINOPYRIMIDINE SULFATE?

    Our copy of the EU Safety Gate database currently contains no alerts linking TETRAAMINOPYRIMIDINE SULFATE to a cosmetic recall. The database is refreshed regularly from the European Commission's official Safety Gate system.

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